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What is laboratory information management system? 

Published By Sanjana
 2018080807:57:04
Category LIMS
                                            

An Introduction to LIMS Software:

Laboratory Information Management System (LIMS) is software that is used in labs for data management and to process a large number of lab samples to manage laboratory workflow. With LIMS, the lab can automate workflows, integrate instruments, and manage samples and associated information. Additionally, labs can produce valid results quickly and can track data across experiments to improve efficiency.

LIMS that are commonly used in clinical labs fall under the following categories:


The benefits of using LIMS Software in your lab are:

  • Workflow automation
  • Integrate instruments or other in-lab systems
  • Centralize access and storage of data
  • Track data from sequencing runs
  • Initiate downstream data analysis

The Efficiency of LIMS System:

The main purpose of using the LIMS System in a lab is to improve the efficiency of sample processing and management. Using LIMS would cut down on the need for manual tasks thereby increasing the accuracy of sample analysis. LIMS captures data automatically, gets processed, and is stored for future reference. The LIMs vendor you choose will define the proceeding process of the software.

Generally, the process of a LIMS is divided into five stages:

  • The sample is logged in after reception.
  • Assignment, scheduling, and tracking of the sample and the analytical workload.
  • Processing and quality control associated with the sample.
  • Storage of data associated with the sample analysis.
  • Inspection, approval, and compilation of the sample data for report generation and further analysis.

Types of LIS Modules Used In Clinical Laboratory:

The features of Laboratory Information System (LIS) have seen evolutionary growth over the years from sample tracking to enterprise resource planning for clinical and specialty laboratories.

A typical workflow pattern of a LIS in a clinical lab flows through three phases:

  • Pre-analytical: Specimen collection.
  • Analytical: testing of the specimens.
  • Post-analytical: Result review.

The LIS modules are used by various laboratory departments like:

  • Blood Bank
  • Immunology
  • Hematology
  • Microbiology
  • Clinical chemistry
  • Histopathology

Various Common Functionalities Used In LIMS:

With the progress in technology, the functions of a LIMS progress too. LIMS software is built in a way to support any upcoming progress while effectively working on a basic set of definite functionalities like the collection of data, tracking of samples, processing, data storage, and report generation.

Some of the core functionalities of LIMS are explained below:

Sample Management:

LIMS was created to help in the process of sample management systems occurring in laboratories. This system gets initiated when a sample is received in a laboratory and gets registered in a LIMS. Since a large number of samples are collected and analyzed in a day, it would be difficult to record the samples without the chance of being confused with other analyses. With LIMS, It would be easier to track the sample if it is labeled and assigned correctly by using RFID on the samples or barcodes.

The information collected and stored via a LIMS would fall under the following criteria:

  • Details about the person whose sample is taken.
  • Details of the doctor/clinic who recommended an analysis.
  • The tests/analysis needed to be taken on the sample.
  • Stages of the sample and destination.
  • Storing procedures.
  • Expected report generation date.
  • Record creation for future purposes.

Workflow Management:

The need for workflow management using a LIMS is as important as Sample management and record-holding. The accuracy of a working system does not just depend on the data; it needs an on-point process assessment where a LIMS system can be used. As the name indicates, workflow management helps automate workflows and assign work if delegated precisely in the software.

All you would have to do for better workflow management using LIMS is:

  • Enter proper codes to direct the LIMS system for a work assignment.
  • Configure the process flow of the work for sample analysis.
  • Assign exact instruments for the particular work.

Workflow management using a LIMS saves time and conducts the job with precision.

EMR/EHR Software:

Electronic Medical Record (EMR) / Electronic Health Record (EHR) is software that collects and stores information on the patient’s medical history in the form of records that can be shared via different healthcare mediums. Many LIMS have this EMR/EHR Software functionality built-in in their system. Using a LIMS with an EHR function will be a huge asset to your lab as the real-time data exchange can be made possible easily.



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Effective Steps to Manage Laboratory Information Management System (LIMS) Software


Upgrading your clinical laboratory might be the latest enhancement you are implementing in your lab. This upgrade means you are automating the key functions to easily maintain the workflow. To make sure that your systems work in a smooth, harmonized, and safe manner, consider installing a cloud-based Laboratory Information Management system in your Lab. The cloud-based LIMS is no doubt the best choice to make as it has many advantages. A few of these are:

  • The data stored in the cloud are fully encrypted, hence 100% data safety.
  • Cost saving as there is no need for server maintenance.
  • With effective data recovery, any data loss can be reverted.
  • No manpower is required as everything is stored in the cloud, unlike physical servers.

Below are some simple tips to effectively manage your Cloud-based Laboratory Information Management System:



Implement a Cloud-Based Service Desk:


The most important step to do while implementing a cloud-based LIMS system is to provide a mini web page for clients to find information that caters to the needs of every patient. The internet is the influence king of the virtual world; so most of your patients will visit your website first, before heading over to your lab. Set up a cloud-based service desk and assist your patients just like you would do in your physical laboratory premises.

Make sure the webpage has a live chat facility so your customers can chat about the types of tests they can do and laboratory locations. Providing a live chat facility can help you to follow up in case the customers log out of the page suddenly. Also, features such as patient portals and customer portals empower your customers to download reports through the website making them completely independent.

Ease of Mobility:


Investing in a LIMS mobile app or website is the biggest advantage that Cloud-based servers can provide a laboratory. Since the data is stored at a remote location and is not bound by the constraints of physical hardware on the premises, investing in a mobile version of your laboratory’s website or even an App is a good idea.

You can take patient satisfaction to another level when you offer your patients and potential patients the ease to reach or access their health information on the go. With a virtual service desk in place, going mobile would mean more and better interactions and increased patient satisfaction.

LIMS Software Staff Training:


It’s essential to train laboratory staff to unlock the full power of your LIMS software application. To utilize LIMS software effectively, you can segregate the employees, departments wise, and provide training accordingly. Delegating one person as the head of training in every department can take the responsibility of providing LIMS-related knowledge sharing and periodic training. LIMS software training can include configuration options, storage, and retrieval of data, managing your workflows, and reporting. Staff training in each department is very important for businesses to succeed.

Increase Speed of Operation:


LIMS Software, specifically designed for laboratory information management, plays a pivotal role in optimizing operations. With a focus on pathology lab software, LIMS efficiently monitors various aspects such as Sample monitoring, sample workflow processes, patient visit count, inventory flow, cash flow, consultant performance, and overall business fluctuations over time. Through the analysis of these metrics, LIMS issues performance-based documents and develops standard quality indicators and key performance indicators, providing a comprehensive solution for laboratory management.

Additionally, Cloud-based LIS (Laboratory Information System) enhances the speed of laboratory operations. While technology facilitates remote meetings, Cloud-based LIS goes a step further by enabling access to data from any location, granting the user the necessary access rights. This feature ensures a swift exchange of information, contributing to an overall increase in the speed of laboratory operations. By seamlessly connecting personnel across different locations, the Cloud-based LIS becomes a valuable asset in streamlining workflows and promoting efficiency within the laboratory environment.

Ease up the Implementation Process and Quality Indicators:


The constant check of quality to ensure stability in business is a major requirement for any industry. With clinical laboratory, it is more of a service quality check rather than product one. Hence, quality indicators are of utmost importance to a laboratory.

LIMS Software, specifically designed for laboratory information management, can efficiently monitor various aspects of laboratory operations such as Sample monitoring, sample workflow process, patient visit count, inventory flow, cash flow, consultant performance, and overall business fluctuations over a period. The system analyzes these metrics to issue performance-based documents, and through the utilization of cloud technology, LIMS can develop standard quality indicators and key performance indicators.

By integrating a cloud-based LIMS System into your laboratory functions, you can optimize processes and identify areas for improvement. This innovative solution allows you to identify and understand your business metrics, paving the way for enhanced business optimization through the power of cloud technology. Whether it's managing sample workflows or evaluating consultant performance, the inclusion of LIMS Software, tailored for pathology lab software, brings a comprehensive and efficient approach to managing laboratory operations.

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As labs are updated and become more modern, better methods of data management and record-keeping may be necessary to maintain or improve efficiency.  Luckily, there is a means to achieve this: Laboratory Information Management Systems, or LIMS.

With the increase in disease and the growth in the medical diagnosis sector, the number of samples collected is increasing day by day. With the help of Machine interfacing, labs can handle a large volume of samples easily, increasing the efficiency of sample processing and the quality of lab reports.

Types of Machine Interfacing in Laboratory Information Management System(LIMS):


Uni-Directional Instruments:

Overview: Uni-directional instruments operate on a one-way communication system, facilitating the seamless transfer of information from the samples to the Laboratory Information Management System (LIMS). In this setup, results are stored within the LIMS database upon the completion of the test process. Unlike bi-directional instruments, which support two-way communication, uni-directional instruments focus on unidimensional data flow.

Workflow Process: The workflow involves manual sample placement by the technician, who assumes the responsibility of strategically positioning samples for analysis. Additionally, the technician plays a crucial role in determining the specific type of sampling method to be employed. This hands-on approach ensures that the instrument receives accurate and relevant data for subsequent processing.

Result Storage: Upon completion of the test, the results are systematically stored in the LIMS database. This unidirectional flow of information simplifies data management, with the LIMS acting as a centralized repository for comprehensive result storage. This streamlined process contributes to the efficiency of data retrieval and analysis within the laboratory setting.

Technician Involvement: The technician's involvement is pivotal in the uni-directional instrument setup, as they guide the initial placement of samples and make informed decisions about the sampling technique. This level of manual intervention ensures precision and control over the testing process, aligning with the laboratory's specific requirements and protocols.

Uni-directional instruments, by emphasizing one-way communication and manual input from skilled technicians, contribute to a structured and controlled laboratory environment where data accuracy and integrity are paramount.

Bi-directional Instruments:

Advanced Functionality: Bi-directional instruments represent a higher level of sophistication and advancement in laboratory technology. These instruments possess the capability to not only generate output data reports and results but also feature an Application Programming Interface (API). This advanced functionality enables the seamless exchange of data, information, commands, functions, and worklists with the system.

Output Data Reports: One key feature of bi-directional instruments is their ability to generate comprehensive output data reports. These reports provide a detailed analysis of test results and relevant information, offering a comprehensive view of the findings. The generated reports serve as valuable documentation for further analysis and decision-making processes.

Results Generation: Bi-directional instruments excel at producing accurate and timely results. The dual communication capabilities allow for efficient data transfer, ensuring that results are not only generated promptly but also transmitted seamlessly to the designated system or database.

Application Programming Interface (API): A defining feature of bi-directional instruments is the inclusion of an Application Programming Interface (API). This interface facilitates the exchange of data, information, and commands between the instrument and the broader laboratory system. The API functionality enhances interoperability, enabling the instrument to import and export data with ease.

Enhanced Connectivity: Bi-directional instruments contribute to enhanced connectivity within the laboratory ecosystem. The ability to import data, information, commands, functions, and worklists through the API fosters a dynamic and integrated environment. This connectivity streamlines laboratory processes, promoting efficiency and accuracy in data handling.

Our LIMS System sends commands to the sampling unit on the type of sampling to be conducted with the given sample. After the testing is done by the LIMS command, the results are auto-fetched on the LIMS Server. The bi-directional instruments are interfaced with the LIMS system programmatically.

The Need to Interface Instruments with LIMS Software:


There are several reasons why it is beneficiary to interface lab instruments with LIMS Software. Let us look into a few reasons here:

Increase in Productivity by Effective Machine Utilization:

Interfacing your instruments with your LIMS Software is a one-time investment of cost and work with a repetitive increase in lab productivity and effectiveness. Interfacing LIMS Software with your lab instruments removes many complexities like manual entering of data every time or referring data from other instruments to the LIMS. This altogether saves a lot of time and effort when done by a LIMS rather than manually, also avoiding any human errors during data entry.

Utilizing machines effectively can increase productivity drastically.  When the task is done manually, very few samples are completely analyzed in the given period, but with MI they can perform many sample processing and that will increase machine utilization and increase revenue.

Increase in Data Quality by Reducing Manual Errors:

The second best reason for interfacing your lab instruments with your LIMS Software is the increase in data quality and integrity. As a human, we are eligible to commit human errors that might not be over-influential over the system as a whole but might still be considered an error. By removing human interference, these errors are avoided thereby guaranteeing better data transfer in the system.

Similarly, transcribing data into the system by people can also lead to common errors affecting the quality of data. Data integrity is considered a very important issue in laboratories. By interfacing your instruments to your LIMS System, you will eliminate this issue.

Saves Time in output generation thereby satisfying the patients:

Machine Interfacing helps to analyze the given samples at a faster rate and generates quality results within a shorter duration of time. After the result processing is done, the report will be generated manually.

With the use of MI, ultimate patient satisfaction can be achieved by generating the results in a quick manner with good quality.

Machine interfacing in laboratories is more of a comfort rather than a negative factor. What might be a one-time investment in your labs can save a lot of time and work when interfaced properly with your systems.

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In every industry, modern laboratories are under pressure to enhance operational efficiency, decrease costs, control regulatory compliance, and improve quality. Apart from this, the rise of CRO (Contract Research Organization) and R&D externalization strategies in the industry of pharmaceuticals has led to laboratories gathering enormous data from different partners, preceding a significant increase in the complexity of lab workflow.


LIMS (Laboratory Information Management System) and informatics Solutions are being used in the pharmaceutical industry to meet these challenges. The main reason why cloud-based LIMS is preferred is due to its advanced features like 

● Decreased cost,

● Automatic software updates,

● Disaster and backup recovery services,

● Rapid implementation of LIMS,

● Flexibility,

● Security,

● Accessibility,

● Collaborations. 


One of the successful Laboratory solutions and laboratory report software used by most users is SaaS. Let's explore the SaaS in depth below. 


What is SaaS?

SaaS(Software as a Service), is one of the software distribution models and types of cloud computing like IaaS and PaaS. The third-party provider hosts the program rather than downloading and installing the software to run on your PC. Once the software is hosted, it's accessed over the internet by users via a web user interface.


Why SaaS, a cloud-based LIMS, is perfect for your lab? 

SaaS, pathology management software provides plenty of excellent benefits that make it the preferred option of every lab. According to the Forrester Research Inc. survey held last year, 15% of SMB (Small to Medium Businesses) and 16% of the larger organizations make use of SaaS. Compared to the previous year's research, the larger enterprise has seen a 33% increase in the Usage of SaaS. Considering the smaller enterprise, they have seen a 50% increase in SaaS. Below are some reasons to state why Cloud-based LIMS is the right option for your laboratory. 


Hosting Options:

Few providers provide the private cloud option that can host within your facility. The private cloud option offers different SaaS LIMS benefits but with fewer security risks. A cloud is public; either it can be private, single-tenant, or multi-tenant. It's easier to validate the single-tenant cloud when compared to the multi-tenant as they are less prone to intrusion or data leakage. 


Data Integrity and Audit Trails:

A permanent audit trail is vital for addressing different concerns in data integrity, both from the perspective of product and regulatory quality. You need to ensure that your SaaS LIMS holds a detailed and reliable audit trail for every piece of information. You also need to make sure that the data is maintained continuously on the various servers rather than on the data itself.

Apart from that, you need to ensure that your provider has set their system default to store a completely reliable and flexible audit trail. It also controls the network logs and detailed server. It offers data center third-party auditing insurance. You need to ensure your SaaS LIMS is capable of integrating with the other informatics systems and with your instruments.


Service Level Agreement:

You must develop a Service Level Agreement with your provider who will be able to address all of the above-concerned areas and more. A Service Level Agreement that is well written is capable of making the variation between a smooth execution & roll out of your SaaS time overruns, cost, and a few of the unexpected expenses incurred.


Security:

When dealing with a SaaS Laboratory Management System, you will depend upon your providers to secure your pieces of information as it is going to be stored in the cloud. Almost every cloud service provider offers excellent security for your valuable data.

Even though the data breach risk is less, few organizations that belong to heavily regulated areas hesitate to enable their information to move away from their firewall. Make sure you have evaluated the policies of your security thoroughly. It means you have your data secured adequately before working with SaaS LIMS.


Validation:

The important compliance responsibility with every regulation resets with the service provider or manufacturer. Most of the vendors advertise these cloud-based SaaS LIMS as a prevalidated system. But this refers to the network of cloud providers. You need to ensure that you get clear about the meaning of the prevalidated system by the vendor. Also, you need to know what scope is covered so that you can know your system is executed in the right way in the user environment.

Apart from that, SaaS LIMS cloud providers handle every clinical laboratory software patch and upgrade. It ensures that you utilize the system's recent version. You need to understand who should manage revalidation once there is an upgrade or patches take place. 


Business Continuity:

You need to understand how data recovery and backup can be handled, and also explore who is the reason and responsible for it. The details of the guarantee like service, response time, hardware, uptime, etc. provided by the provider should be stated clearly in the SLA (Service Level Agreement). Apart from that, the Service Level Agreement should contain the details of recovery and backup services that are included. Also, it should hold the cost incurred by exploring a few of the optional services.


System Failover:

There can't be anyone who didn't use Google. For instance, what will happen in case a rogue asteroid crashes into the server farms of Google? Nothing happens. Airtight failover technology and Mirrored servers indicate that the news service will display the crater's aerial photos, which once acted as the server farm. High availability and uptime are included in the terms & conditions of the cloud deals that are negotiated in any form.


Instrument Interfacing:

The complexity of the SaaS LIMS is challenging. Private, hosted, and On-Premises cloud LIMS is capable of handling instrument interfacing in the same manner. It is difficult to understand the SaaS LIMS cloud providers' ability, track record, and philosophy when you deal with the instrument interface.


Economics of Scale:

SaaS LIMS cloud providers provide you with more or less due to the technology's specialized use. As many customers utilize identical resources at the same cost, data centers, are slashed, and then the savings are passed to the customer. 


Bottom Line:

In the past few years, technology providers have developed cloud-based SaaS LIMS based on market demand. SaaS LIMS enables to facilitate enhanced scalability, agility, innovation, and connectivity across the lab environment. It helps to increase efficiency in operation as well as decrease cost. The decision to make use of a cloud-based SaaS LIMS will be taken into step by a mix of various concerns like regulatory, operations, and security. The best way to ensure that your corporation benefits the higher from a SaaS approach to a laboratory information management system is to work with a top-notch informatics consultant.

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Going wrong in experiments taking place in laboratories is usual, but proper attention and planning can help prevent damaged reputations, wasted resources, and unnecessary accidents. Below are some reasons why laboratories fail and what can be done to stop them. 

A shortfall of orientation with the Business:
Bell Labs, Xerox PARC, and other legendary labs can evoke images of complete isolation and extreme secrecy from the core business. Split-up sorting is significant in the case of organizations where rules and regulations head to balance new ideas. In this case, split-up remains as a rare problem. 
The issue inclines that the labs do not have a clear strategy planned with the organization. You can see most of the labs offers kombucha by installing kegs on tap to acquire the creative things beginning and then start to evaluate with only a finite conception of their goals. Some of the team in the labs are not sure that they are charged with disruption or serving the core business. 

The committee members and leaders should consider the importance of opening a lac, decide on how the lab will benefit or interrupt the present and future Business, should plan for a remedy in the case of disruption, prepare the works for how the new ideas are going to be executed, and more. The planning and other steps can be successful if it's made with the following considerations. 

  • Vitality: Making clear and creative goals for the lab will assist both company leaders and stakeholders in understanding the intent and direction of the development vision. 
  • Growth: Let's imagine, you have come up with an idea that is validated as well as requires growing outside of the lab. Now, where will you get the additional support for the plan? There are a few options like going back to an accelerator, an incubator, or into the core business. Possibly, troublemaking innovations will go outside of the core enterprises, as it can be developed in a further way and also secured from business-as-usual fingerprints and corporate antibodies. 
  • People: People with purpose and passions are considered to be the heart of the most influential development initiatives as there is no chance for the lab to support the stakeholders who come up with new ideas and implement them in unchartered territory. 

Lack of team balance: 
Some people have good intentions and knowledge of the industry but fail as they do not have any idea how innovation works. Possibly, the leaders of this type deal with the development and changes as they deal with a problem in the core business. This will lead to more significant incremental improvements. 
The other way the lab fails is when they are staffed merely by a team of external tycoons, whose only thinking is to set fire to conventional forms of operating burns bridges along with the organization. It means the people know the steps to build a business or launch startups but will miss the internal networks and knowledge needed to handle corporate networks. 

It's essential to take a diverse team to be more successful at your organization. You also need people outside the enterprise, but you need to make sure that they possess different skills including employees for long with a passion for development, creativity and also should know the working nature of the company. 
It's not much easy to maintain this balance, but you need to make it happen. The practical development team in or out of the lab needs to be diverse and purpose-driven in terms of background, function, and cognitive style. 

The shortfall of metrics to trace success: 
Innovation needs unique and creative thinking around economic support. Labs require space to incubate, evolve, or iterate new ideas. Return and financial need to be tracked over time and also should be insisted in advance even if your lab acts as a cost center that is mandated to experiment over the longer term. 

Apart from this, there are some other essential things for the laboratories failing like Undervaluing ROI (Return on Investment), hiring extremes, building vs buying, meaningless hackathons, inflated expectations, the CTO/CINO/CIO dilemma, undue focus on interruption, poor project management, a big plan with no stepping stones, ignoring people by focusing on technology, and more. 

Do you have any other suggestions to stop the laboratories from failing?
For more information visit MocDoc LIMS Software

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